Selegiline or L-Deprenyl (trade names include Eldepryl; Emsam; Deprenyl; Anipryl; Egibren; Jumex; Jumexil; Moverdin; Selegos; Selgian; Selgin; Zelapar) is an antiparkinsonian drug from monoamine oxidase type B (MAO-B) inhibitors pharmacological group. This medication is used to treat symptoms of Parkinson's disease, parkinsonism, shaking palsy, paralysis agitans, such as dementia in Alzheimer's disease, shakiness (tremor), muscle stiffness, loss of normal movement, sudden switching between normal movement and stiffness, other movement disorders. This is a cognitive enhancing smart anti aging drug that improves brain functions, cognitive actions, concentration, the range of motion and ability to walk, dress, exercise. Selegiline works by increasing and extending the effects of levodopa, and helping to slow the progress of Parkinson's disease. Deprenyl is usually used in combination with other antiparkinson medications (e.g., levodopa, carbidopa).
Emsam (Selegiline in the form of transdermal patch) is prescribed for the therapy of depression and major depressive disorder.
This medication is also indicated to treat the symptoms of Cushing's disease and cognitive dysfunction in veterinary medicine for dogs, pets and animals.
Selegiline was tested and studied for the treatment of attention deficit hyperactivity disorder (ADHD); to stop smoking tobacco or cannabis.
Pharmacological and medical categories:
Anti aging drugs
Pharmaceutical drugs for the treatment of Parkinson's disease
Central nervous system agents
Dopaminergic antiparkinsonism agents
Meds to treat ADHD
Monoamine oxidase B (MAO-B) inhibitors
Stop smoking pills
Veterinary medications, pet meds
The Anatomical Therapeutic Chemical (ATC) classification system codes:
N - Nervous system
N04 - Anti-parkinson drugs
N04B - Dopaminergic agents
N04BD - Monoamine oxidase B inhibitors
N04BD01 - Selegiline
The International Statistical Classification of Diseases and Related Health Problems (ICD-10, World Health Organization) codes:
Cushing's syndrome - E24
Dementia in Alzheimer's disease ( G30.-+ ) - F00*
Cannabis related disorders - F12
Major depressive disorder, single episode - F32
Major depressive disorder, recurrent - F33
Attention-deficit hyperactivity disorders - F90
Parkinson's disease - G20
Other specified degenerative diseases of nervous system - G31.8
Mild cognitive impairment, so stated - G31.84
Tobacco abuse counseling - Z71.6
B2 - Australia
C - United States (Risk cannot be ruled out)
Salts and other forms used as active pharmaceutical ingredients (API):
Xilopar - Teva; Cephalon; Elan Pharmaceuticals; Esteve; Segix Italia
Zelapar - Teva; B & S Healthcare; Cardinal Health; Cephalon; Elan Pharmaceuticals; Lexon UK; Servipharm; Star Pharmaceuticals; Valeant Pharmaceuticals; Zeneus Pharma
Some other medications in the same pharmacological classes:
Almirid (Dihydroergocryptine Mesylate)
Sinemet (Carbidopa; Levodopa)
Stalevo (Carbidopa; Entacapone; Levodopa)
Here is a list of popular medications containing Selegiline as a main active pharmaceutical ingredient; their trade names, forms, doses, companies - manufacturers, distributors, suppliers, researchers and developers:
Trade name of the drug
Pharmaceutical forms and doses
Tablets; Oral; 5 mg
Capsules; Oral; 5 mg
Syrup; Oral; 10 mg / 5 ml
Tablets; Oral; 5 mg
Tablets; Oral; 10 mg
Transdermal Systems; Topical; 6 mg / 24 h
Transdermal Systems; Topical; 9 mg / 24 h
Transdermal Systems; Topical; 12 mg / 24 h
Tablets; Oral; 5 mg
1. What you need to know about Selegiline from The Drug Classroom:
2. How Selegiline (Deprenyl) Slows Brain Aging from Bentham Science:
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